DHT is an abbreviation of Dihydrotestosterone or (5Alpha-Dihydrotestosterone). So, what is DHT. It is a male hormone or an androgen. The enzyme 5 alpha-reductase, found in the adrenal glands; hair follicles; testes and prostate, is responsible for synthesising DHT.
This is present in both men and women, but more men are affected than women, see under the male pattern baldness in women section.
In some people there appears to be a genetic predisposition to have an over sensitivity to the DHT, which results over time in the shrinkage of the hair follicle; shorter lifespan of hair, and production of abnormal fine hair shafts, rather than seeing the usual thick mature telogen hair shaft (older hair found in the resting phase of hair growth cycle). This in turn gives the appearance of baldness, and it tends to occur in a pattern, hence it’s name.
The dermal papilla is the most important part of the hair follicle as it is responsible for the growth of hair. The papilla is in direct contact with blood capillaries bringing blood, oxygen, and nutrients to it for good hair growth. However, the papilla also has a large number of androgen receptors on it (more in males leading to an increase in this type of baldness), where the DHT can attach itself and undermine the absorption of vital oxygen and nutrients. In turn, this leads to longer resting phases and shorter growing phases in the life cycle of the hair, thus the hair becomes lighter, finer and smaller until it is vellus.
DHT levels in the body can be affected by medical conditions, such as benign prostatic hyperplasia (BPH). A great deal of research is happening with Saw Palmetto for prostatic growths (benign and cancerous) which not only benefits the prostate but is of great benefit in hair regrowth and alopecia treatment, this will be discussed in the section, saw palmetto hair loss.
Invisi Hair provides a variety of DHT blocking hair restoration products and services.